As the author grew up in American Indian culture, she didn't develop any interest in Native American culture. This fact can't be something like doubt or satisfaction or concern and also presumptuousness/brazen/failed to observe something.

Therefore, the answer should be (A) irony in

There is some (i) _______ the fact that the author of a book as sensitive and informed as Indian Artisans did not develop her interest in Native American art until adulthood, for she grew up in a region rich in American Indian culture.


One would expect an author of a book that was sensitive to the subject matter (apart from being well informed) to be interested in it since childhood, especially if the subject matter was the very culture she grew up in. But we are told that she became interested in it only in her adulthood. This is very unexpected and therefore, the correct word is irony in.

An irony is a state of affairs or an event that seems deliberately contrary to what one expects and is often wryly amusing as a result