OE

C, E

The blank in this sentence describes “[t]hose scholars” who like a type of math that is “intrica[te] and esoteric” and is attempted by “those who have mastered the prerequisite topics.” From this, you can infer that the formulas of geometric topology are challenging to understand, and you might expect these scholars to be fascinated by its formulas. However, the detour road sign “notwithstanding” contrasts how they respond to the formulas with “the undeniable appeal” of the subject. Thus, despite their enthusiasm for geometric topology, predict that they feel confused by the formulas. Confounded, (C), means “perplexed,” and nonplussed, (E), means “unsure what to do.” These words both match the prediction and give the sentence the same sense. Elated, (A), means “very happy.”
This is how these scholars feel about difficult math in general but not about the formulas as discussed in this sentence. Inveigled, (B), means “lured by flattery.” While these mathematicians are attracted by certain math topics, geometric formulas are not capable of deceit. Moreover, this word does not correspond to the detour road sign “notwithstanding.” There is no indication that the mathematicians are unimpressed, (D), or oppressed, (F).