The best way I've found to get rid of a zit overnight is either with ALOT of zit cream piled on that zit or a more natural remedy that usually works is to take baking soda and mix it with water to make a paste. Then take the paste and put a layer on the zit let it dry then go to bed. Its really effective at drying out zits and it also gets rid of oily or shiny areas if you use it right before you go out. Hope that helps!