6⁸ − 3⁸ is a DIFFERENCE OF SQUARES. So we can factor it.
6⁸ − 3⁸ = (6⁴ + 3⁴)(6⁴ - 3⁴)
= (6⁴ + 3⁴)(6² + 3²)(6² - 3²)
= (6⁴ + 3⁴)(6² + 3²)(6 + 3)(6 - 3)
= (6⁴ + 3⁴)(45)(9)(3)
= (6⁴ + 3⁴)(3)(3)(5)(3)(3)(3)

Hmmmm, we can see that the correct answer is "hiding" in the first number (6⁴ + 3⁴)
Let's factor out the 3⁴, to get:
6⁴ + 3⁴ = 3⁴(2⁴ + 1)
= 3⁴(16 + 1)
= 3⁴(17)
= (3)(3)(3)(3)(17)

So, 6⁸ − 3⁸ = (3)(3)(3)(3)(17)(3)(3)(5)(3)(3)(3)

So the correct answer is C

Cheers,
Brent